Efudix cream 0.5% 20g Tube, Fluorouracil
THIS IS A BRAND MEDICATION
Efudix cream contains the active ingredient fluorouracil, which is a type of medicine known as a cytotoxic antimetabolite. Fluorouracil is a chemotherapy medicine used to treat cancer. Efudix cream is applied to the skin to treat skin cancer and skin conditions that can develop into cancer (pre-malignant skin lesions).
Cancers form when cells within the body multiply abnormally and uncontrollably. These cells spread, destroying nearby tissues. Fluorouracil works by stopping cancerous and pre-cancerous cells from multiplying. It does this by being incorporated into the cells' genetic material, DNA and RNA. Both DNA and RNA are needed for cells to grow, repair themselves and multiply. Fluorouracil causes problems with the production of DNA and RNA in the cancerous cells and this causes them to grow in an unbalanced way, resulting in the death of the cells.
Fluorouracil cream will cause the area of the skin being treated to become red, blotchy and inflamed. This will probably be followed by some discomfort, skin erosion and eventually, healing. Healing may not be complete until one or two months after you stop using the cream. The cream should not damage normal healthy skin. However, Efudix will treat abnormalities of the skin that were not previously visible to the naked eye, and these abnormalities may become red and inflamed.
If your skin causes you a lot of discomfort during the treatment you should tell your doctor, as this can usually be eased by using a corticosteroid cream.